Don't forget drug use. Hard drugs tend to age you still love her thoughyeah, I would definitely bet that her looking old is more due to her surgery and whatnot
Edit: just wanted to add that even though the article on PGPR is meant to be fear-mongering, it doesn't have that effect on most people with a chemistry background. "a yellowish, viscous liquid comprised of polyglycerol esters of polycondensed fatty acids from castor oil"... you could easily describe a broccoli in this way if you so wished. Just read these articles with a grain of salt.
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